Download release 19.0 of the NCBI protein profile Hidden Markov models (HMMs) used by the Prokaryotic Genome Annotation Pipeline (PGAP). You can search this collection against your favorite prokaryotic proteins to identify their function using the HMMER sequence analysis package.
What’s new?
Release 19.0 contains:
- 18,513 HMMs maintained by NCBI
- 465 new HMMs since release 18.0
You can search and view the details for these in the Protein Family Model collection, which also includes conserved domain architectures and BlastRules, and provides access to all RefSeq proteins that these models name.
Future changes
To reduce space on FTP, older data directories will be modified by the release process (from release 20.0 onwards). The five previous releases will continue to have their entire data available. For older releases, the directories will be modified so that the individual HMM and SEED directories are removed, since the data is still contained within the corresponding HMM and SEED tarball files.
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Please reach out to us if you have questions or would like to provide feedback.