Tandem Mass Spectrometry

A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.

Year introduced: 2007

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Tree Number(s): E05.196.566.880

MeSH Unique ID: D053719

Entry Terms:

• Mass Spectrometry, Tandem
• Mass Spectrometry-Mass Spectrometry
• Mass Spectrometry Mass Spectrometry

Previous Indexing:

• Spectrum Analysis, Mass or specifics (1981-2006)

All MeSH Categories
Analytical, Diagnostic and Therapeutic Techniques and Equipment Category
Investigative Techniques
Chemistry Techniques, Analytical
Mass Spectrometry
Tandem Mass Spectrometry